Nasjonal oversikt over covid-19-studier

Basert på innsamlede opplysninger fra helseregionene og deres underliggende miljøer vil det kontinuerlig oppdateres en nasjonal oversikt over covid-19-studier.

Nye studier meldes via questback.

Oversikten viser registrerte forskningsprosjekter (startet/planlagt) i spesialisthelsetjenesten som gjelder covid-19 pasienter. Oversikten er delt inn i 3 tabeller; behandlingsstudier, observasjonsstudier og andre.

I perioden etter registreringen vil trolig flere prosjektledere innlemme nye samarbeidspartnere og prosjektet endre status fra planlagt til pågående. For at listen til enhver tid skal være oppdatert ber vi om at prosjektledere melder slike endringer i e-post til NorCRIN@helse-bergen.no

Først publisert: 03.04.2020
Sist oppdatert: 20.12.2021
Antall nye studier: 2
Totalt antall studier: 126

Study design: Treatment
(11 studies)

Registrated (month/year)	Project status	Project leader/Contact info	Health trust/Institution	Study title/Aims of the study	Study design	Ethics approval	Biobank	Funding	Patient categories	Total number of patients to be included	Age of patients	Collaborative institutions	Regional health trust
03/2020	Completed	Olav Dalgard	Akershus Universitetssykehus	Norwegian coronavirus disease 2019 (NO COVID-19) study: An open labeled randomized controlled pragmatic trial evaluate the antiviral effect of chloroquine in adult patients with SARS-COV-2 infection	Treatment	Yes	Yes	Yes	Hospitalized patients without intensive care	200	>18 years		Helse Sør-Øst
04/2020	Planning	Tormod Fladby	Akershus Universitetssykehus	Controlling IFN responses for CoV Protection and adjuvant Treatment (CICPaT) – an adaptive, two-stage open label, pragmatic randomized controlled trial in hospitalized adults diagnosed with COVID-19	Treatment	No			Intensive care patients/Hospitalized patients without intensive care	150	>18 years	The Norwegian Institute of Public Health University of Oslo	Helse Sør-Øst
03/2021	Ongoing	Catherine Joyce Teig	Akershus Universitetssykehus	Treating patients with anal incontinence using remote patient monitoring (RPM) during a pandemic	Treatment	Yes	No	No	Outpatients	60	18-90 years old		Helse Sør-Øst
04/2020	Ongoing	Pål Aukrust	Oslo Universitetssykehus	WHO: The NOR Solidarity multicenter trial on the efficacy of different anti-viral drugs in SARS CoV-2 infected patients ClinicalTrials.gov	Treatment	Yes	Yes	Yes	Intensive care patients			International multicenter study	Helse Sør-Øst
04/2020	Ongoing	Lise Sofie Nissen-Meyer	Oslo Universitetssykehus	Open randomized controlled phase 2 clinical trial for evaluation of safety and efficacy of COVID-19 convalescent plasma compared to standard care for treatment of COVID-19 disease among elderly	Treatment	Yes	Yes	Yes	Inpatients other institutions	Approx 500	>50 years	National multicenter study including blood banks, nursery homes and COVID-19-dedicated primary care institutions in several health regions.	Helse Sør-Øst
04/2020	Ongoing	Hanne Scholz	Oslo Universitetssykehus	Placenta-derived Decidual stromal cells (DSC) in the treatment of acute pulmonary disease	Treatment	Yes	Yes	Yes	Hospitalized patients without intensive care				Helse Sør-Øst
04/2020	Ongoing	Fridtjof Heyerdahl	Oslo Universitetssykehus	Inhaled NO as bridge to rapid sequence intubation in COVID-19 related hypoxemia (INOCOV-19)	Treatment	Yes	No	Yes	Hospitalized patients without intensive care				Helse Sør-Øst
04/2020	Ongoing	Jon Henrik Laake	Oslo Universitetssykehus	Handling oxygenation targets in adults with COVID-19 associated acute hypoxaemic respiratory failure in the ICU	Treatment	Yes	No	Yes					Helse Sør-Øst
04/2020	Ongoing	Anders Åsberg	Oslo Universitetssykehus	Pharmacokinetic population analysis of antiviral drugs in the NOR SOLIDARITY study	Treatment	Yes	Yes	Yes					Helse Sør-Øst
09/2020	Ongoing	Arne Vasli Søraas	Oslo Universitetssykehus	Cod Liver Oil for COVID-19 Prevention Study	Treatment	Yes	Yes	Yes	Outpatients	80000			Helse Sør-Øst
12/2021	Ongoing	Anne Margarita Dyrhol Riise	Oslo Universitetssykehus	A Phase 1/2 Study to Determine Safety and Immunogenicity of Two COVID 19 Vaccines VB10.2129 (RBD Candidate) and VB10.2210 (T Cell Candidate) Previously Vaccinated in Healthy Adult Volunteers	Treatment	Yes	No	Yes		160	18-60 years old	Haukeland University Hospital	Helse Sør-Øst

Study design: Observational
(84 studies)

Registered (month/year)	Project status	Project leader/Contact info	Health trust/Institution	Study title/Aims of the study	Study design	Ethics approval	Biobank	Funding	Patient categories	Total number of patients to be included	Age of patients	Collaborative institutions	Regional health trust
03/2020	Ongoing	Jørgen Dahlberg	Akershus Universitetssykehus	ICU triage	Observational	Yes		Yes	Intensive care patients	Approx 90	All patients assessed for intensive care treatment	Oslo University Hospital	Helse Sør-Øst
03/2020	Planning	Jonn Terje Geitung	Akershus Universitetssykehus	Radiology of Covid patients	Observational	No	No		Intensive care patients/Hospitalized patients without intensive care/Outpatients	1-5	50-100		Helse Sør-Øst
03/2020	Ongoing	Christopher Inchley	Akershus Universitetssykehus	COVID-19 in hospitalised Norwegian children – risk factors, outcomes and immunology	Observational	Yes	Yes	Yes	Intensive care patients/Hospitalized patients without intensive care/Outpatients	250	≤ 18 years	University Hospital of North Norway; St Olavs Hospital; Oslo University Hospital; Stavanger University Hospital; Østfold Hospital; Vestre Viken Hospital; Fonna Health (Haugesund Hospital); Haukeland University Hospital, Bergen; Health Møre and Romsdal (Ålesund Hospital); Innlandet Hospital (Lillehammer); Nordland Hospital (Bodø); Norwegian Institute of Public Health	Helse Sør-Øst
03/2020	Ongoing	Torbjørn Omland	Akershus Universitetssykehus	Mekanismer bak sykelighet og dødelighet ved COVID-19 ClinicalTrials.gov	Observational	Yes	Yes	Yes	Intensive care patients/Hospitalized patients without intensive care	200	>18 years		Helse Sør-Øst
2020	Ongoing	Torbjørn Omland	Akershus Universitetssykehus	Use of blood pressure medication and risk of COVID-19 infection and complications	Observational	Yes	No	Yes					Helse Sør-Øst
03/2020	Ongoing	Gunnar Einvik	Akershus Universitetssykehus	Patient reported outcomes and lung function after hospitalization for COVID-19 infection (PROLIFE)	Observational	Yes	No	Yes	Intensive care patients/Hospitalized patients without intensive care	500	>18	Akershus University Hospital, University of Oslo, Landsforeningen for Hjerte- og lungesyke, Oslo Universitetssykehus (OUS), Sykehuset Østfold Kalnes (SØ), Haukeland universitetssykehus (HUS), St. Olavs Hospital	Helse Sør-Øst
04/2020	Planning	Anne Eskild	Akershus Universitetssykehus	The SARS Cov-2 epidemic among pregnant women and pregnancy outcomes	Observational	No			Outpatients	50 000	30	Departments of Microbiology in Norway	Helse Sør-Øst
04/2020	Ongoing	Tormod Fladby	Akershus universitetssykehus HF	Controlling IFN responses for CoV Protection and adjuvant Treatment (CICPaT)	Observational	Yes	Yes	Yes	Intensive care patients/Hospitalized patients without intensive care	200	>18 years	The Norwegian Institute of Public Health University of Oslo	Helse Sør-Øst
05/2020	Ongoing	Silje Bakken Jørgensen	Akershus universitetssykehus	Covid-19 infections in health care workers with different levels of exposure to SARS-CoV-2 infected patients (COVPROTECT)	Observational	Yes	Yes	No	Outpatients	400	adults		Helse Sør-Øst
07/2020	Ongoing	Knut Stavem	Akershus universitetssykehus	Patient-reported outcomes and thromboembolism after COVID-19 without hospitalization (PROTROM)	Observational	Yes	No	Yes	Outpatients	900	>18	Akershus University Hospital, Østfold Hospital, Fürst laboratory	Helse Sør-Øst
07/2020	Planning	My Svensson	Akershus universitetssykehus	Pulmonary ultrasound as a diagnostic tool in patients with COVID-19 infection	Observational	Yes	No	No	Hospitalized patients without intensive care	40	Above 18		Helse Sør-Øst
03/2021	Ongoing	Vegard Bruun Bratholm Wyller	Akershus universitetssykehus	Long-term effects of COVID-19 in adolescents (LoTECA)	Observational	Yes	Yes	No	Outpatients	500	12-25 years old
03/2021	Ongoing	Torbjørn Omland	Akershus universitetssykehus	Covid-19 og langtidsskader på hjertet	Observational	Yes	No	No	Outpatients	100	>18		Helse Sør-Øst
04/2020	Planning	Grethe Åstrøm Ueland	Bergen/Noklus/Norwegian diabetesregistry for Adults	Patient reported outcome measures (PROMS) in patients with diabetes mellitus type I og II under the Covid-19 pandemic 2020	Observational	Yes			Intensive care patients/Hospitalized patients without intensive care/Outpatients	10 000 with type 1 diabetes and 19 000 with type 2 diabetes	18 – 100 år	The Norwegian diabetes registry for adults collects data from all health regions in Norway	Helse Vest
03/2020	Ongoing	Marius Myrstad	Bærum sykehus Vestre Viken HF	Covid-19 at BæRum hospital – Acute care and outcomes (The COBRA-study)	Observational	No		Yes	Intensive care patients/Hospitalized patients without intensive care	All patients admitted to hospital with covid-19	18 years and older		Helse Sør-Øst
03/2020	Finalised	Hans Flaatten	Haukeland Universitetssjukehus	Prognostic factors in criticall ill patients with COVID-19 infection ≥ 70 years. A multicenter international study: COVIP ClinicalTrials.gov	Observational	Yes	No	Yes	Intensive care patients	1346 (total no. of included patients)	≥70	10 hospitals in Norway, including all region hospitals. 28 countries and 139 ICUs throughout Europe & Israel	Helse Vest
03/2020	Ongoing	Hilde Engjom	Haukeland Universitetssjukehus	COVID19 in pregnancy- Norway	Observational	Yes	No	Yes	Intensive care patients/Hospitalized patients without intensive care/Outpatients			National Advisory Unit for Womens’s Health and the Norwegian Institute of Public Health	Helse Vest
03/2020	Ongoing	Rebecca Cox	Haukeland Universitetssjukehus	COVID-19 infection in the general population and health care workers	Observational	Yes		Yes	Intensive care patients/Hospitalized patients without intensive care/Outpatients/Inpatients other institutions	2500	0-100	Haukeland University Hospital, University in Bergen, Haraldsplass Hospital, Bergen Kommune, Stavanger University Hospital	Helse Vest
04/2020	Ongoing	Cecilie Svanes	Haukeland Universitetssjukehus/ Universitetet i Bergen	Susceptible to Covid-19	Observational	No		Yes	Outpatients	200	about 20-70 years	Haukeland Universityhospital and University of Bergen	Helse Vest
06/2020	Planning	Arvid Steinar Haugen	Haukeland universitetssykehus, Helse Bergen	Assessment of teamwork, communication and consistency of care in surgical teams during the Severe Acute Respiratory Syndrome – Corona Virus 2 pandemic	Observational	Yes	Yes	No	Hospitalized patients without intensive care	600	>18	(Recruiting)	Helse Vest
03/2020	Ongoing	Eystein Husebye	Helse Bergen	Observational study of Covid-19 infections in patients with primary adrenal insufficiency	Observational	Yes	No	Yes	Outpatients	100	18 and above	All somatic hospitals in Norway	Helse Vest
03/2020	Ongoing	Oddbjørn Hove	Helse Fonna HF	Teleconsultation for adults with developmental disabilities	Observational	No		Yes	Outpatients	50	18+		Helse Vest
04/2020	Ongoing	Kjetil Søreide	Helse Stavanger	CovidSurg ClinicalTrials.gov	Observational	Yes	No	Yes	Intensive care patients/Hospitalized patients without intensive care	2500?	>18 years	Global, international, currently >150 countries	Helse Vest
04/2020	Ongoing	Lise Tuset Gustad	Nord-Trøndelag HF	Clinical characterization of Coronavirus disease (COVID-19) and long-term consequences on individual and communities	Observational	Yes		Yes	Intensive care patients	1200	>18	HNT HF, NTNU, SINTEF, Helse Bergen, University of Michigan	Helse Midt-Norge
04/2020	Ongoing	Arne Vasli Søraas	Oslo Universitetssykehus	Risk factors for community- and workplace transmission of COVID-19 ClinicalTrials.gov	Observational	Yes	No	Yes					Helse Sør-Øst
04/2020	Ongoing	Kristin Hofsø	Oslo Universitetssykehus	Survival rates and long-term outcomes for patients with COVID-19 admitted to Norwegian ICUs	Observational	Yes	No	Yes	Intensive care patients				Helse Sør-Øst
04/2020	Ongoing	Mette Kalager	Oslo Universitetssykehus	COVID-19 Public Response and Rapid-Cycle Re-Implementation of Activities	Observational	Yes	No	Yes					Helse Sør-Øst
04/2020	Ongoing	Kjetil Sunde	Oslo Universitetssykehus	Intensive medicine priority decisions during the COVID-19 pandemic (INTENSIVE TRIAGE)	Observational	Yes	No	Yes	Intensive care patients				Helse Sør-Øst
04/2020	Ongoing	Lars Wik	Oslo Universitetssykehus	Use of self-report and sensors for monitoring clinical parameters during home isolation of patients with COVID-19 infection	Observational	Yes	No	Yes	Outpatients				Helse Sør-Øst
2020	Ongoing	Tine Grimholt	Oslo Universitetssykehus	The aims are to study a representative sample of Norwegian people, their quality of life, stress and coping strategies during the first phase of the corona outbreak in Norway	Observational	Yes	No	Yes					Helse Sør-Øst
05/2020	Ongoing	Tine Grimholt	Oslo Universitetssykehus	Mental reactions to COVID-19 among adults with heart failure	Observational	Yes	No	Yes	Intensive care patients/Hospitalized patients without intensive care/Outpatients/Inpatients other institutions	2000	Adults		Helse Sør-Øst
04/2020	Planning	Lene Bergendal Solberg	Oslo Universitetssykehus	Longitudinal population-based environmental seroepidemiological investigation protocol for COVID-19 virus infection in healthcare workers in an orthopeadic emergency department	Observational	No	Yes						Helse Sør-Øst
04/2020	Ongoing	Elfrida Hartveit Kvarstein	Oslo Universitetssykehus	Vulnerable patients with personality disorder – consequences of the corona crisis	Observational	Yes	No	Yes	Outpatients				Helse Sør-Øst
04/2020	Ongoing	Jan Cato Holter	Oslo Universitetssykehus HF	Norwegian SARS-CoV-2 study ClinicalTrials.gov	Observational	Yes	Yes	Yes	Intensive care patients/Hospitalized patients without intensive care	1000 or more	18 years and older	8 hospitals in Norway, including all region hospitals, taking part in ISARIC COVID-19 Global data collaborative	Helse Sør-Øst
2020	Ongoing	Maria Stylianou Korsnes	Oslo Universitetssykehus	COVID-19 impact on patient care	Observational	No	No	Yes					Helse Sør-Øst
2020	Finalised	Peter Monrad-Hansen	Oslo Universitetssykehus	Appendicitis presentation and treatment before and after COVID-19; business as usual, or delay?	Observational	No	No	Yes					Helse Sør-Øst
2020	Ongoing	Kristian Tonby	Oslo Universitetssykehus	COVID-19 OUS. Kvalitetsregister for alle pasienter innlagt ved Oslo Universitetssykehus med COVID-19 sykdom	Observational	No	No	Yes					Helse Sør-Øst
2020	Ongoing	Margrethe von Tangen	Oslo Universitetssykehus	Retrospektiv vurdering av triagering av Covid-19 pasienter ved bruk av nytt Kap 41: Mistanke om Corona-infeksjon	Observational	No	No	Yes					Helse Sør-Øst
2020	Planning	Trond H. Diseth	Oslo Universitetssykehus	How to prevent social isolation and psychosocial dysfunction in the general child population and in children with chronic/severe somatic diseases facing the COVID-19 pandemic	Observational	No	No						Helse Sør-Øst
2020	Ongoing	Søren Pischke	Oslo Universitetssykehus	Prevalence of complement activation in COVID-19 patients admitted to OUS	Observational	No	No	Yes					Helse Sør-Øst
2020	Ongoing	Kristin Bjordal	Oslo Universitetssykehus	Development of an international questionnaire to assess patient-reported symptoms and concerns related to COVID-19 disease, the COVID-19 QLQ-##	Observational	No	No	Yes					Helse Sør-Øst
2020	Ongoing	Stig Evensen	Oslo Universitetssykehus	COPSYC-19: Consequences for patients with psychosis from the SARS-CoV-2 shut-down	Observational	Yes	No	Yes					Helse Sør-Øst
2020	Ongoing	Jostein Skjalg Hagemo	Oslo Universitetssykehus	Prehospital treatment of «silent hypoxia» in young patients COVID-19	Observational	Yes	No	Yes					Helse Sør-Øst
2020	Ongoing	Erik Koldberg Amundsen	Oslo Universitetssykehus	Laboratory diagnostics for risk stratification in COVID-19	Observational	Yes	Yes	Yes					Helse Sør-Øst
2020	Ongoing	Åslaug Helland	Oslo Universitetssykehus	SARS-CoV-2 and Cancer	Observational	Yes	No	Yes					Helse Sør-Øst
2020	Ongoing	Irene Lie	Oslo Universitetssykehus	A Norwegian study on views and experiences of health care professions working in intensive care units during the COVID-19 pandemic	Observational	Yes	No	Yes					Helse Sør-Øst
2020	Ongoing	Suraj Bahadur Thapa	Oslo Universitetssykehus	Psychological distress and Coping in Psychiatric Patients during COVID-19 pandemic (PsyCo-COVID-19): A cross-sectional study at Oslo University Hospital	Observational	Yes	No	Yes					Helse Sør-Øst
2020	Planning	Arne Eltvedt Fiane	Oslo Universitetssykehus	EuroECMO-COVID	Observational	No	No						Helse Sør-Øst
2020	Ongoing	Ludvig Munthe	Oslo Universitetssykehus HF	Defining the immune cells that correlate with fatal acute lung injury in COVID-19	Observational	No	Yes	Yes					Helse Sør-Øst
05/2020	Ongoing	Hilde Wøien	Oslo Universitetssykehus HF	Delirium in critically ill patients with SARS-CoV-2 infection	Observational	No	No	Yes	Intensive care patients	1000			Helse Sør-Øst
2020	Ongoing	Kristin Lie Romm	Oslo Universitetssykehus HF	COPE – Corona pandemic experiences by patients with psychotic – and bipolar disorders	Observational	Yes	No	Yes	Hospitalized patients without intensive care/Outpatients	300			Helse Sør-Øst
05/2020	Ongoing	Ann Lee Solevåg	Oslo Universitetssykehus HF	Visitor bans in hospitals: How are newborn infants affected during the COVID-19 pandemic?	Observational	Yes	Yes	Yes	Intensive care patients/Hospitalized patients without intensive care	300	Infants		Helse Sør-Øst
06/2020	Ongoing	Anne Hege Aamodt	Oslo Universitetssykehus HF	The Norwegian study of nervous system manifestations and sequelae in COVID-19 (NeuroCOVID)	Observational	No	Yes	Yes	Intensive care patients/Hospitalized patients without intensive care				Helse Sør-Øst
06/2020	Ongoing	Karsten Midtvedt	Oslo Universitetssykehus HF	COVID IgG KTx	Observational	Yes	Yes	Yes	Intensive care patients/Hospitalized patients without intensive care/Outpatients/Inpatients other institutions	3700			Helse Sør-Øst
08/2020	Ongoing	Lise Sofie Nissen-Meyer	Oslo Universitetssykehus HF	NORPLASMA monitor	Observational	Yes	No	Yes	Intensive care patients	50			Helse Sør-Øst
08/2020	Planning	Vasilis Sitras	Oslo Universitetssykehus HF	COVID-19 in Pregnancy, Childbirth and Puerperium (COVID-Preg-ChiP Study)	Observational	Yes	Yes	No	Outpatients	200	Pregnant women		Helse Sør-Øst
08/2020	Ongoing	Randi Opheim	Oslo Universitetssykehus HF	Views of patients with inflammatory bowel disease on the COVID-19 pandemic and the health care service – a Quality study	Observational	No	No	Yes	Hospitalized patients without intensive care	1000			Helse Sør-Øst
08/2020	Ongoing	Ellen Ruud	Oslo Universitetssykehus HF	Effect of the COVID19 pandemic on pediatric cancer incidence at Oslo University Hospital	Observational	No	No	Yes	Intensive care patients/Hospitalized patients without intensive care/Outpatients	90	>18		Helse Sør-Øst
09/2020	Ongoing	Nina M. Kynø	Oslo Universitetssykehus HF	Pandemic 2020 – Parental debut in isolation	Observational	No	No	Yes	Intensive care patients	25			Helse Sør-Øst
09/2020	Planning	Kirsti Tøien	Oslo Universitetssykehus HF	Visiting restrain to hospitals; family caregivers of COVID-19 ICU-patients experiences. An exploratory study	Observational	No	No	Yes					Helse Sør-Øst
10/2020	Ongoing	Ansgar Heck	Oslo universitetssykehus HF	COVID-19 in patients with pituitary disease	Observational	Yes	Yes	Yes					Helse Sør-Øst
03/2021	Planning	Hanne Birgit Alfheim	Oslo universitetssykehus HF	Corona virus-related visitation restrictions enforced in ICUs in the Scandinavian countries – what can we learn to meet future challenges?	Observational	No	No	No					Helse Sør-Øst
03/2021	Ongoing	Elisabeth Bø	Oslo universitetssykehus HF	Physiotherapy treatment of hospitalised patients with COVID-19 at Oslo University Hospital	Observational	No	No	No	Intensive care patients/Hospitalized patients without intensive care	500
03/2021	Ongoing	Ane Gerda Z. Eriksson	Oslo universitetssykehus HF	Influence of the COVID-19 pandemic on women with gynecological cancer	Observational	No	No	No	Outpatients	1500
03/2021	Ongoing	Ann Færden	Oslo universitetssykehus HF	The COVID-19 pandemic: Reactions from of acutely ill psychiatric patients	Observational	No	No	No	Hospitalized patients without intensive care	50
03/2021	Planning	Ann Færden	Oslo universitetssykehus HF	The COVID-19 pandemic: Reactions from mental health workers in the acute psychiatric department	Observational	No	No	No					Helse Sør-Øst
03/2021	Ongoing	Arne Kolstad	Oslo universitetssykehus HF	Monitoring of immunological response to COVID-19 vaccine in lymphoma/leukemia patients treated with anti-CD20 monoclonal antibodies and in patients who have completed allogenic stem cell transplantation	Observational	Yes	Yes	No	Hospitalized patients without intensive care/Outpatients	200			Helse Sør-Øst
03/2021	Ongoing	Bjørn Moum	Oslo universitetssykehus HF	Secure IBD registry. Surveillance epidemiology of Coronavirus (COVID-19) under research exclusion.	Observational	No	No	No	Hospitalized patients without intensive care/Outpatients	10	Yes	International database	Helse Sør-Øst
03/2021	Planning	Lise Sofie Nissen-Meyer	Oslo universitetssykehus HF	Blood donor screening anti-SARS-CoV2	Observational	Yes	Yes	Yes, OUS					Helse Sør-Øst
03/2021	Ongoing	Andreas Seierstad	Oslo universitetssykehus HF	COVID-19 and labor market participation for young adults with psychosis	Observational	No	No	No	Outpatients	6			Helse Sør-Øst
03/2021	Ongoing	Ketil Stordal	Oslo universitetssykehus HF	COVID-19 and children in BERET-19	Observational	No	No	No	Hospitalized patients without intensive care				Helse Sør-Øst
2020	Ongoing	Oliver Distler Local contact OUS: Anna Hoffmann-Vold	Zürich University hospital, Switzerland	COVID-19 in the EUSTAR cohort of systemic sclerosis	Observational	No	No	Yes					Helse Sør-Øst
2020	Ongoing	Grete Dyb Local contact OUS: John-Anker Zwart	Norwegian Center for Violence and Traumatic Stress Studies, Universitetet i Oslo	Stress responses and health complaints among hospital staff working in intensive care units and clinical wards during the COVID-19 pandemic	Observational	No	No	Yes					Helse Sør-Øst
2020	Planning	Margrethe Greve-Isdahl Local contact OUS: Per Kristian Knudsen	Norwegian Institute of Public Health, Oslo	MINI-Nor Maternal and Infant Immunity against Vaccine Preventable Diseases in Norway	Observational	No	No						Helse Sør-Øst
2020	Ongoing	Local contact OUS: Geir E. Tjønnfjord	Memorial Sloan Kettering Cancer Center, New York	Examining COVID19 Course and Outcomes in Patients Previously Diagnosed with Chronic Lymphocytic Leukemia	Observational	No	No	Yes					Helse Sør-Øst
04/2020	Ongoing	Erik Solligård	St. Olavs hospital	CUT COVID-19 Coronaundersøkelsen Trøndelag – Risk stratification of severe COVID-19 infection in children and adults	Observational	Yes		Yes	Intensive care patients/Hospitalized patients without intensive care	2000	0-100 years	Helse Nord-Trøndelag, Helse Møre og Romsdal, NTNU, UNN	Helse Midt-Norge
12/2021	Ongoing	Ragna Elise Støre Govatsmark	St. Olavs hospital	Effekt av Covid-19 pandemien på innleggelse og behandling av hjerteinfarkt i Norge	Observational	No	No	No	Intensive care patients/Hospitalized patients without intensive care/Inpatients other institutions	80000		OUS, Haukeland, UNN, Arendal sykehus, Ahus, Volda sjukehus	Helse Midt-Norge
04/2020	Planning	Line Pedersen	St. Olavs and Sørlandet Hospital	Home monitoring and followup og COVID-19 patients	Observational	No			Hospitalized patients without intensive care/Outpatients	200	From 18 and up.	St.Olavs Hospital and Sørlandet Hospital	Helse Midt-Norge
03/2020	Planning	Torbjørn Moe Eggebø	Stavanger universitetssjukehus	Covid-19 infection in pregnancy	Observational	No			Outpatients	4000	18-50		Helse Vest
04/2020	Ongoing	Ingvil Mjaaland	Stavanger universitetssjukehus	Kvalitetsoppfølging av pasienter med tidlig brystkreft som får endret fraksjonering i strålebehandling som følge av Covid-19 pandemien.	Observational	No		Yes	Outpatients	30 patients, maybe more if the pandemic lasts longer	18 years or older		Helse Vest
08/2020	Ongoing	Anne Kristin Møller Fell	Sykehuset Telemark	The Corona and COVID-19 study in Telemark and Agder	Observational	Yes	Yes	Yes	Outpatients	5000	18 and older	Sørlandet Sykehus	Helse Sør-Øst
04/2020	Ongoing	Christine M. Jonassen	Sykehuset Østfold	Viral factors associated with severe cases of COVID-19	Observational	No		Yes	Intensive care patients/Hospitalized patients without intensive care/Outpatients/Inpatients other institutions	150	>18		Helse Sør-Øst
03/2020	Planning	Gernot Ernst	Vestre Viken HF, Kongsberg sykehus	Loss of olfaction as an early predictor for the development of critical COVID-19 infections	Observational	No			Outpatients	200	>18		Helse Sør-Øst
03/2020	Planning	Gernot Ernst	Vestre Viken HF, Kongsberg sykehus	Heart Rate Variability as prognostic factor in patients with COVID-19 infection	Observational	No			Intensive care patients/Hospitalized patients without intensive care	60	>18		Helse Sør-Øst

Study design: Other
(31 studies)

Registered (month/year)	Project status	Project leader/Contact info	Health trust/Institution	Study title/Aims of the study	Study design	Ethics approval	Biobank	Funding	Patient categories	Total number of patients to be included	Age of patients	Collaborative institutions	Regional health trust
04/2020	Ongoing	Espen Saxhaug Kristoffersen	Akershus universitetssykehus HF	Neurology during the pandemic (NeuroPan)	Other	No	No	Yes		100-150	>18 years	Oslo University Hospital and Haukeland University Hospital	Helse Sør-Øst
05/2020	Ongoing	Espen Saxhaug Kristoffersen	Akershus universitetssykehus HF	Stroke during a pandemic (StrokePan) study	Other	Yes	No	Yes	Hospitalized patients without intensive care	350	17-100		Helse Sør-Øst
03/2021	Ongoing	Hege Vangstein Aamot	Akershus universitetssykehus HF	Whole genome sequencing of SARS-CoV-2 virus: CoV-seq	Other	Yes			Intensive care patients/Hospitalized patients without intensive care/Outpatients				Helse Sør-Øst
04/2020	Ongoing	Ingrid Miljeteig	Helse Bergen	Priority dilemma, moral distress and support experienced by physicians and nurses in Helse Vest during the COVID-19-epidemic	Other	Yes		Yes				University of Bergen	Helse Vest
07/2020	Ongoing	Dagny Faksvåg Haugen	Helse Bergen	Experience of end-of-life care during the Covid-19 crisis	Other	Yes	No	Yes		Maximum 292 participants in Norway	>18	Erasmus University Medical Centre, Rotterdam (lead) and partners in several other countries	Helse Vest
04/2020	Planning	Harleen Grewal	Helse Bergen og Universitet i Bergen	Cohort study of COVID-19 Nested within a Randomised Controlled Trial of Patients Hospitalised with Community Acquired Pneumonia: Disease severity, Optimised management, and Outcomes	Other	Yes			Hospitalized patients without intensive care	Uncertain, would depend upon the evolution of the epidemic.	Adults ≥18 years	Copenhagen University, Leiden University (Netherlands), University of Southampton (UK)	Helse Vest
2020	Planning	Mette Tollånes	Universitetet i Bergen	Protokoll for utprøving av immunologiske hurtigtester for COVID-19	Other	No	No						Helse Vest
04/2020	Ongoing	Arne Broch Brantsæter	Oslo Universitetssykehus	Serum standard for COVID-19 vaccine	Other	No	Yes	Yes					Helse Sør-Øst
04/2020	Ongoing	Anders Åsberg	Oslo Universitetssykehus	COVID-19 outcome in patients with chronic kidney disease	Other	Yes	Yes	Yes	Hospitalized patients without intensive care				Helse Sør-Øst
04/2020	Ongoing	Gunnveig Grødeland	Oslo Universitetssykehus	Novel vaccine development against COVID-19	Other	Yes	No	Yes					Helse Sør-Øst
04/2020	Ongoing	Tom Mala	Oslo Universitetssykehus	Abdominal pain in COVID-19 patients	Other	Yes	No	Yes	Hospitalized patients without intensive care				Helse Sør-Øst
04/2020	Ongoing	Marius Rehn	Oslo Universitetssykehus	Pre-hospital management of COVID-19	Other	No	No	Yes	Hospitalized patients without intensive care				Helse Sør-Øst
04/2020	Ongoing	Tom Hemming Karlsen	Oslo Universitetssykehus	An anonymized GWAS to urgently query host genetic predisposition to severe COVID-19 (SARS-CoV-2 infection) lung disease	Other	Yes	Yes	Yes	Hospitalized patients without intensive care				Helse Sør-Øst
04/2020	Planning	Arne Klungland	Oslo Universitetssykehus	Epitranscriptomic regulation of viral fitness upon SARS-CoV-2 infection; a host-virus study	Other	No	No						Helse Sør-Øst
04/2020	Planning	Stefan Krauss	Oslo Universitetssykehus	Pharmacological WNT inhibition to attenuate the cytokine storm, the central severe complication in COVID-19 infections	Other	No	No						Helse Sør-Øst
04/2020	Planning	Fridtjof Lund-Johansen	Oslo Universitetssykehus	COVID-19 immunity in the population	Other	No	No						Helse Sør-Øst
04/2020	Ongoing	Ludvig Munthe	Oslo Universitetssykehus	Establishing in tube-diagnostic tests for immunity or susceptibility for SARS-CoV-2 in elderly cancer patients and in high-risk children	Other	No	No	Yes					Helse Sør-Øst
04/2020	Ongoing	Karl Øyri	Oslo Universitetssykehus	Research and Development for a low-cost, quickly produced mechanical ventilator capacity scaling system for Covid-19 affected communities	Other	No	No	Yes					Helse Sør-Øst
04/2020	Planning	Charles Ethan Paccione	Oslo Universitetssykehus	The Mind-Body App for Mental Health Management	Other	No	No						Helse Sør-Øst
04/2020	Planning	Simon Rayner	Oslo Universitetssykehus	Integrated novel intervention strategies for COVID-19 : Using data mining to fight current and future pandemics	Other	No	No						Helse Sør-Øst
04/2020	Planning	Tone Tønjum	Oslo Universitetssykehus	Reversing COVID-19 (RevCOVID-19)	Other	No	No						Helse Sør-Øst
2020	Ongoing	Atle Bjørnerud	Oslo Universitetssykehus	Artificial intelligence to quantify important segments from CT in COVID-19	Other	No		Yes					Helse Sør-Øst
2020	Ongoing	Håvard Kalvøy	Oslo Universitetssykehus	Splitting one ventilator for multiple patients	Other	No		Yes					Helse Sør-Øst
2020	Ongoing	Kristin Lie Romm	Oslo Universitetssykehus	REACT-NOR – react now! Remote follow-up of relatives of patients with psychosis during the COVID-19 crisis	Other	No	No	Yes					Helse Sør-Øst
2020	Ongoing	Lars Eide	Oslo Universitetssykehus	COVID-19 general biobank	Other	Yes	Yes	Yes					Helse Sør-Øst
05/2020	Ongoing	Kjetil Taskén	Oslo Universitetssykehus	Immunoregulatory and antiviral properties of compounds derived from anti-malaria drugs as hydroxychloroquine	Other	No	No	Yes					Helse Sør-Øst
05/2020	Ongoing	Eivind Hovig	Oslo Universitetssykehus	Production of «in house» versions of reverse transcriptase and Taq DNA polymerase for use in SARS-CoV-2 assays	Other	No	No	Yes					Helse Sør-Øst
03/2020	Planning	Lars Lien	Sykehuset Innlandet	The impact of the coronavirus disease (COVID-19) outbreak on people with concurrent mental health and substance use disorders	Other	No			Outpatients	25	18-65	VID, HINN	Helse Sør-Øst
04/2020	Ongoing	Lars Petter Bjørnsen	St. Olavs hospital Universitetssykehus Trondheim	Ultralydsdiagnostikk av mistenkt COVID-19 smittede pasienter i akuttmottaket	Other	Yes	No	Yes	Hospitalized patients without intensive care	200	Over 16 år	Sørlandet sykehus HF, St Olavs hospital, Haukeland Universitetssykehus, Oslo universitetssykehus Ullevål, Nordlandssykehuset HF Bodø, Drammen sykehus, Sykehuset Telemark HF Skien, Stavanger universitetssykehus, Akurshus universitetssykehus	Helse Midt-Norge
05/2020	Ongoing	Hege Selnes Haugdahl	Helse Nord-Trøndelag HF	Isolated and critically ill – experiences of video-communication between ICU family members and ICU nurses and physicians during the Covid-19 disease	Other	No	No	Yes	Intensive care patients	8-12 ICU family members		UiT The Arctic University of Norway	Helse Midt-Norge
04/2020	Ongoing	Waleed Ghanima	Sykehuset Østfold	Research biobank for internal medicine	Other	Yes		Yes	Intensive care patients/Hospitalized patients without intensive care/Outpatients				Helse Sør-Øst